CBD mafuta uye hemp zvinyorwa

Munguva pfupi yapfuura, kufarirwa kwekugadzirira kwe cannabis kwakawedzera zvakanyanya. Kushamwaridzana ne cannabis kunogona kunge kwakakonzera chikamu kune iyi maitiro. Nekudaro, zviri pamutemo zvehemp zvinowanikwa nemafuta eCBD hazvina kufanana nembanje nekuti hazvina chinodhakisa THC. Muchinyorwa ichi, tichapindura mibvunzo inotevera: chii hemp, chii chinonzi CBD mafuta, anowanikwa sei, chii chinozivikanwa nezve maitiro avo pamuviri wemunhu?

Dr. N. Pharm. Maria Kaspshak

Cherechedza: Ichi chinyorwa ndechezvinangwa zvemashoko, haisi nzira yekuzvirapa, haisi uye haigoni kutsiva kubvunzurudzwa kwemunhu nachiremba!

Hemp chirimwa chave chirimwa kwemazana emakore

Hemp, kana Cannabis sativa, chirimwa chakarimwa chinowanikwa pasi rose. Sezvinoita chero chirimwa, kune akawanda subspecies uye marudzi e cannabis, imwe neimwe iine yayo yakasarudzika maitiro. Hemp yakarimwa kwemazana emakore nekuda kwemafibers ayo, anoshandiswa kugadzira tambo, tambo uye tow, pamwe nemachira (saka iwo marudzi ehemp). Mafuta ehemp aitorwa kubva kumbeu, iyo yaishandiswa pakudya uye maindasitiri - semuenzaniso, kugadzira pendi uye varnish. Panyaya iyi, hemp ine mashandisirwo akafanana neflax (iyo inorimwa zvakare kune fiber nembeu dzemafuta), uye donje risati raunzwa kuEurope, flax nehemp ndidzo dzainyanya kukonzeresa tambo dzechirimwa dzembatya nezvimwe zvigadzirwa. Chinhu chinonakidza ndechekuti kusati kwapararira kurimwa kwembesa muPoland, yaive mafuta ehemp, padivi pemafuta emafuta uye, isingawanzo, mafuta embeu yepoppy, aive mafuta emuriwo ainyanyozivikanwa mumaruwa ePoland. Kushandiswa kwemafuta emiriwo kwainyanya kufarirwa panguva yeAdvent neLent, apo mafuta emhuka aitsanya uye asingapedzi.

Hemp, hemp, mbanje - chii chakasiyana?

Parizvino, hemp inofarira sechirimwa chemishonga. Kunyanya kukosha munyaya iyi ndeye inflorescences yevakadzi, yakafuma mune biologically inoshanda zvinhu, kunyanya cannabinoids (kana: cannabinoids) uye terpenes. Mushonga unokonzera narcotic effect ye cannabis ndeye delta-9-tetrahydrocannabinol (THC), iyo inodhaka iyo inokonzera manzwiro euphoria, kuzorora, kuchinja kwemaonero echokwadi, nezvimwewo. Nechikonzero ichi, THC uye cannabis ine zvinopfuura 0,2 .XNUMX% THC maererano nehuremu hwakaoma, vanoonekwa semushonga muPoland, uye kutengesa kwavo nekushandisa hazvisi pamutemo.

Cannabis (Cannabis sativa subsp. Indica, cannabis) ine huwandu hwakanyanya hweTHC. Mhando dzeCannabis dzine yakaderera kuomeswa kweTHC inorondedzerwa seindasitiri hemp (Cannabis sativa, hemp), haina zvinhu zvinodhakisa, uye kurima kwavo nekutengesa hazvirambidzwe. Kunyangwe cannabis uye maindasitiri cannabis mhando dzemhando imwe chete, kana maviri akasiyana marudzi, hapana chibvumirano chakazara, asi kune avhareji mushandisi, iyo botanical kupatsanurwa haisi iyo inonyanya kukosha.

Cannabinoids uye terpenes phytochemicals inowanikwa mu cannabis

Cannabis sativa ine trace uwandu hweTHC, asi kune mamwe macommunication akaiswa cannabinoids (kana cannabinoids), kusanganisira CBD - cannabidiol (cannabidiol) uye terpenes, i.e. zvinhu zvinowanikwa muzvirimwa zvakawanda zvine hunhu, hwema hunofadza. CBD haina zvinhu zvinodhakisa zvevanhu uye haina kupindwa muropa. Iyo cannabinoids uye terpenes ye cannabis inonyanya kunyura mune glandular bvudzi rinokura pane echikadzi inflorescences. Kubuda kwadzo, uye hemp resin ine zviumbwa izvi, zvinonamira zvakanyanya uye zvinogona kudzivirira chirimwa kubva pakuoma uye kukura kwehutachiona kana chakanganiswa.

Terpenes, senge pinenes, terpineol, limonene, linalool, myrcene (nemamwe akawanda) makomisheni anowanikwa kwete mu cannabis chete, asiwo mune zvimwe zvirimwa zvakawanda, kunyanya izvo zvine kunhuhwirira kwakasimba. Izvo zvinosanganiswa mumafuta mazhinji akakosha echisikigo uye zvinonhuwira, pamwe nekunhuhwirira kwakawedzerwa kune zvizorwa. Vamwe vavo vane antibacterial properties inodzora kugaya uye bile secretion (somuenzaniso, alpha- uye beta-pinene). Zvisinei, anogona kukonzera allergies, saka vanorwara neallergy vanofanira kuzvishandisa nekuchenjerera.

Kurapa mhedzisiro ye cannabinoids - mishonga ine THC uye CBD

Cannabinoids inobata pamuviri wemunhu kuburikidza neanonzi cannabinoid receptors, anowanikwa kunyanya mutsinga uye mumasero ekudzivirira muviri. Aya ma-receptors chikamu cheimwe ye "yekukurukurirana uye nzira dzekudzora" mumuviri, senge opioid receptors nevamwe. Iyo endocannabinoid sisitimu mumuviri inotonga akati wandei mabasa emuviri senge manzwiro uye chishuwo pamwe nemhinduro yekudzivirira uye inokanganisa endocrine system. Tetrahydrocannabinol (THC) inobata zvakasimba zvinogamuchirwa muuropi, zvichiita, pakati pezvimwe zvinhu, kunzwa kwekudhakwa. Cannabidiol (CBD) inoita seisina mhedzisiro pa cannabinoid receptors, asiwo kune vamwe, senge histamine. Zvichida zvakare inoshandura mhedzisiro yeTHC.

 Anabinoids vakawana kushandiswa kwavo mumishonga. Mushonga une synthetic THC, dronabinol, wakatenderwa neUS FDA kurerutsira kurutsa uye kunatsiridza kudya mune yakaremara AIDS nevarwere vegomarara. Sativex ine THC uye CBD inowanikwa muPoland uye inoratidzwa kuzorodza kwepasticity (yakawandisa tsandanyama contraction) muvarwere vane multiple sclerosis. Epidiolex ichangobva kubvumidzwa kuumbwa ine yakachena CBD musesame mafuta, inoratidzirwa kurapwa kwemamwe marudzi epfari muvana - Dravet syndrome uye Lennox-Gastaut syndrome. Haisati yave kuwanikwa muPoland.

Mafuta eHemp nemafuta eCBD - anei uye anowanikwa sei?

Mafuta ehemp akanyanya mafuta kubva kumbeu dzehemp. Icho chigadzirwa chakakosha chekudya, chine kuravira kunofadza uye ine yakakosha unsaturated fatty acids omega-3 uye omega-6 muchiyero chakanaka. Kune rumwe rutivi, mafuta eCBD anowanzoita mafuta ekudyara (hemp kana mamwe) pamwe nekuwedzera kwechidimbu (kubvisa) kubva kune zvikamu zvakasvibirira zvemuti wehemp - mashizha kana maruva. Uye - nekuda kwekuisa kwavo - kuravira kwavo hakuchafadzi.

Chimwe chezvinhu zvakakosha zvechinyorwa ichi cannabidiol (CBD), nokudaro zita remishonga iyi. Zvisinei, hemp extract inewo zvimwe zvinomera zvinhu (kana phytochemicals, kubva muchiGiriki "phyton" - chirimwa), kureva zvimwe cannabinoids, terpenes nezvimwe zvinhu zvakawanda, zvichienderana nemhando yehemp inoshandiswa uye nzira yekubvisa, i.e. extract. Dzimwe nguva vagadziri vanonyora "full spectrum" pane iyo label kuratidza kuti yakazara cannabis yakatorwa yakashandiswa. Organic solvents inogona kushandiswa kubvisa, i.e. "kugeza kunze" uye kusungirirwa kwemakemikari echido kubva kumiti yemiti, sezvo cannabinoids uye mamwe phytochemicals haaputi mumvura. Iyi nzira ine zvipingamupinyi zvayo - masara esolvent anogona kusvibisa chigadzirwa chakapedzwa, uye zvakasara zvacho zvinofanira kuraswa zvakanaka. Ndokusaka iyo inonzi supercritical CO2 kutorwa. Izvi zvinoreva kushandisa mvura carbon dioxide sechinhu chinonyungudutsa pasi pekumanikidzwa kwakanyanya, i.e. mune izvo zvinonzi supercritical conditions.

 Iyi tsananguro yakaoma mumunda wefizikisi yezvimiro zvemuviri, asi chakakosha kwatiri ndechekuti mvura kabhoni dhaikisaidhi inonyungudutsa zvinhu zvisinganyunguduke mumvura, haina chepfu uye, pasi pemamiriro akajairika, inobuda nyore nyore pasina kusiya tsvina. . Saka, iyi supercritical CO2 kudhirowa inzira "yakachena" kwazvo inoshandiswa mumishonga uye maindasitiri ezvekudya.

Dzimwe nguva unogona kuverenga nezve CBD oiri kuti "decarboxylated." Zvinorevei? Zvakanaka, akawanda cannabinoids anogadzirwa nezvirimwa mune acidic fomu. Ngatikuyeuchidzei kubva kuchikoro kuti boka re organic acids iboka re carboxyl, kana -COOH. Kupisa muchero wakaomeswa kana kubvisa kunotyora boka iri kubva kune cannabinoid molecule uye inoiburitsa secarbon dioxide - CO2. Iyi idecarboxylation process kuburikidza iyo cannabidiol (CBD), semuenzaniso, inogona kuwanikwa kubva cannabidiolic acid (CBDA).

Ko mafuta eCBD ane mhedzisiro yekuporesa?

Hemp inotorwa, mishonga yekugadzirira kana mafuta eCBD akafanana neakarongwa gadziriro, senge Epidiolex ine CBD? Aiwa, haana kufanana. Kutanga, ivo havana THC. Kechipiri, Epidiolex ine yakachena cannabidiol yakanyungudutswa mumafuta, iyo yakaedzwa kune chaiyo dosages. CBD oiri ine cocktail yakazara yeakasiyana cannabis makomisheni. Hazvizivikanwi kuti kuvapo kwemamwe phytochemicals kunoshandura sei migumisiro ye cannabidiol pamuviri. Imwe kambani mafuta eCBD inogona kunge iine chimiro chakasiyana zvachose pane cheimwe, sezvo vangashandisa akasiyana hemp strains, nzira dzekugadzira, uye hunhu hwekutonga. Pamusoro pezvo, zvimwe zvidzidzo zvezvekudya zvine mafuta eCBD zvinoratidza kuti izvo zvirimo zvecannabidiol uye zvimwe zvinongedzo zvinogona kusiyana kubva kune zvakaziviswa nemugadziri, sezvo kudzora kugadzirwa kwekuwedzera hakusi pasi pekuoma kwakafanana nekutonga kwekugadzira zvinodhaka. . Iko hakuna zvakare yakakwana miedzo yekiriniki parizvino yekusimbisa kuporeswa kwemafuta eCBD kune zvimwe zvirwere, saka hapana zvakare madhasi akatemerwa anogona kukonzera mimwe mhedzisiro.

Nezvikonzero zvese izvi, maoiri eCBD haagone kutorwa semushonga uye hachisi chokwadi kuti, semuenzaniso, Epidiolex yakafanana neCBD mafuta. Saizvozvowo, willow bark haina kufanana neaspirin. Izvi hazvireve kuti maoiri eCBD haakonzerese muviri uye haachinje zviratidzo zvechirwere - pane zvishoma zvakavimbika, zvakasimbiswa ruzivo nezvenyaya iyi.

Maitiro ekushandisa zvakachengeteka CBD mafuta?

Zvisinei nekushaikwa kwehumbowo hwekiriniki hwekurapa kwemafuta eCBD, ari kuwanikwa pamusika uye ari kuwedzera mukurumbira. Hazvitengeswi sezvinodhaka, asi vanhu vakawanda vanoda kuzviedza. Kana ukasarudza kushandisa CBD oiri, pane mashoma akakosha mitemo yekuchengeta mupfungwa.

• Chekutanga pane zvese, tsvaga emhando yepamusoro CBD oiri kubva kune vanovimbwa vanogadzira. Bvunza nezve chimiro chekunyoreswa kwechigadzirwa, zvitupa zvekuongorora zvinyorwa, zvichida kuitwa nevechitatu-bato marabhoritari.
• Chechipiri, bvunza chiremba wako, kunyanya kana uri kutora mishonga. Cannabidiol uye phytochemicals inogona kudyidzana nemishonga kuderedza kana kuwedzera mhedzisiro yavo kana kukonzera chepfu mhedzisiro. Kune miti yakawanda nemishonga inopesana nemishonga yakawanda (yakadai seSt. John's wort kana grapefruit), saka "zvakasikwa" hazvirevi kuti "yakachengeteka mumamiriro ezvinhu ose."
• Tarisa nemutarisiri wako wehutano kuti uone kana kutora CBD mafuta kunogona kubatsira. Mubhuku rebhaibheri unowana mabviro ekukubatsira kuita sarudzo yako.
• Sarudza huwandu kana kushumira kwemafuta auri kutora nachiremba wako, kunyanya kana iwe uchida kutsigira chirwere chisingaperi chechirwere kana kutora mamwe mishonga. Paunenge uchitarisa huwandu hwemafuta aunotora, rangarira kuti kune maoiri ane akasiyana mazinga uye kudzika kweCBD, sarudza chaiyo gadziriro.
• Kunze kwekunge chiremba wako akuudza neimwe nzira, usapfuure muyero unokurudzirwa nemugadziri.
• Ziva kuti cannabidiol uye mamwe phytochemicals anogonawo kuva nemigumisiro yakaipa pamuviri, kunyanya pamadhora makuru kana nekushandisa kwenguva refu. Vanogona kuva, pakati pezvimwe zvinhu, kurara, kuneta, kushungurudza, matambudziko nechiropa kana itsvo. Panogona kunge paine zvimwe zviitwa zvatisingazive nekuda kwekusaita tsvakiridzo munzvimbo iyi. Tarisa maitiro ako!
• Usashandise mafuta eCBD kana uine matambudziko echiropa kana itsvo, kana uine nhumbu kana kuyamwisa. Nguva dzose bvunza chiremba wako kana usina chokwadi!
• Usamboramba chirevo chachiremba wako uchifarira "kuzviporesa" mafuta eCBD! Kunyanya kana iwe uchirwara zvakanyanya, senge cancer, chirwere chetsinga kana chepfungwa, haufanirwe kuita izvi. Unogona kuzvikuvadza zvakanyanya.

Mabhuku

1. CANNABIDIOL (CBD), Chirevo cheKuongorora Kwakakosha, Komiti Yenyanzvi paKutsamira Kwezvinodhaka, Musangano weFortieth, Geneva, 4-7 June 2018 https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf (dostęp 04.01.2021)
2. Nyaya yeMitemo 2005 Nha. 179, Art. 1485, AWA Act yaChikunguru 29, 2005 yekurwisa kupindwa muropa nezvinodhaka. Zvinongedzo kumutemo nemamwe zviito zvemutemo: https://www.kbpn.gov.pl/portal?id=108828 (zuva rekupinda: 04.01.2021/XNUMX/XNUMX)
3. Ruzivo nezveSativex: https://www.mp.pl/pacjent/leki/lek/88409,Sativex-aerozol-do-stosowania-w-jamie-ustnej (Yakasvika: 04.01.2021/XNUMX/XNUMX)
4. Ruzivo nezve Epidiolex (muChirungu): https://www.epidiolex.com (Yakasvika: 001.2021)
5. Zvinyorwa zvezvidzidzo: VanDolah HJ, Bauer BA, Mauck KF. "Chiremba Chinotungamira kuCannabidiol uye Hemp Mafuta". Mayo Yakachena Proc. 2019 Sep;94(9):1840-1851 doi: 10.1016/j.mayocp.2019.01.003. Epub 2019, Nyamavhuvhu 22. PMID:31447137 https://www.mayoclinicproceedings.org/action/showPdf?pii=S0025-6196%2819%2930007-2 (dostęp 04.01.2021)
6. Arkadiusz Kazula "Kushandiswa kwezvisikwa cannabinoids uye endocannabinoids mukurapa", Postępy Farmakoterapii 65 (2) 2009, 147-160

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